GRDA (formerly FIRDA) on EEG

Generalized rhythmic delta activity (formerly FIRDA) · Slowing · ICU

Runs of synchronous frontal 2 Hz delta on a mildly slow background. Simulated trace, longitudinal bipolar channels. Open in the interactive viewer

What it looks like

Runs of monomorphic, bilaterally synchronous delta, often frontally predominant in adults. The older name was frontal intermittent rhythmic delta activity (FIRDA). 1

What it means at the bedside

A non-specific marker of diffuse encephalopathy: metabolic, toxic, raised intracranial pressure, deep midline lesions. In a large critical-care cohort, GRDA was not associated with seizures, unlike lateralized rhythmic delta (LRDA). 25

EncephalopathyNon-specificNot epileptiform

Sources

  1. Hirsch LJ, et al. American Clinical Neurophysiology Society's Standardized Critical Care EEG Terminology: 2021 version. J Clin Neurophysiol 2021;38:1–29. doi.org/10.1097/WNP.0000000000000806
  2. Rodriguez Ruiz A, et al. Association of periodic and rhythmic electroencephalographic patterns with seizures in critically ill patients. JAMA Neurol 2017;74:181–188. doi.org/10.1001/jamaneurol.2016.4990

Related patterns