Spikes and sharp waves on EEG: focal epileptiform discharges and phase reversal

Interictal epileptiform discharges · Epileptiform

Sharp waves with after-going slow waves, phase-reversing at F7–T7. Simulated trace, longitudinal bipolar channels. Open in the interactive viewer

What it looks like

Transients that stand out from the background, with a sharp peak, an asymmetric rise and fall, an after-going slow wave and a believable field. Spikes last 20–70 ms, sharp waves 70–200 ms; the distinction has no clinical weight. 3,4

What it means at the bedside

In the right clinical setting these support a diagnosis of focal epilepsy; alone they do not make one. Around 0.5% of healthy adults carry epileptiform discharges. 21 Switch montage in the viewer: the phase reversal at F7/T7 in the bipolar chain becomes the largest deflection in the average reference.

EpileptiformLeft temporalPhase reversal

Sources

  1. Kane N, et al. A revised glossary of terms most commonly used by clinical electroencephalographers and updated proposal for the report format of the EEG findings (IFCN, 2017). Clin Neurophysiol Pract 2017;2:170–185. doi.org/10.1016/j.cnp.2017.07.002
  2. Kural MA, et al. Criteria for defining interictal epileptiform discharges in EEG: a clinical validation study. Neurology 2020;94:e2139–e2147. doi.org/10.1212/WNL.0000000000009439
  3. Gregory RP, Oates T, Merry RT. Electroencephalogram epileptiform abnormalities in candidates for aircrew training. Electroencephalogr Clin Neurophysiol 1993;86:75–77. pubmed.ncbi.nlm.nih.gov/?term=Gregory+Oates+Merry+epileptiform+aircrew+1993

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