The Tract — Neurology, written to be remembered

The month in neurology, in two pages.

What changed, how strong the evidence is, and whether it should change what you do on Monday. Free to read, no sign-up needed.

01Tenecteplase before thrombectomy may help cardioembolic stroke more than atheroscleroticStrokeWatch

02The first joint European guideline on infectious encephalitis puts a clock on aciclovirNeuro-infectionChange practice

03ECTRIMS in two minutes: five things from MSToronto2026Multiple sclerosis5 points

04Plasma p-tau217 predicts who becomes impaired — over years, not monthsDementiaNo change

!An accelerated-approval filing for CNM-Au8, built on trials that missed their primary endpointsHype checkHype check

Epilepsy · Bedside

Seizure Compass

Decision support, not a diagnosis.

Estimates how likely an event is to be an epileptic seizure, a functional (psychogenic non-epileptic) seizure, syncope or another mimic, and helps localise seizure onset from semiology — built on published semiology data.

Seizure vs functional seizure vs syncope
Semiology-based localisation
Installs on iPhone and Android

Open Seizure Compass

Critical care · Calculator

Najm ICUCalc

Bedside arithmetic, with its sources.

A bedside ICU calculator: infusion and antibiotic dosing, haemodynamics, ventilator settings, blood gases, electrolytes, renal and fluids, scores, antidotes, RSI and a neuroprotective-strategy panel.

12 sections incl. ABG and electrolytes
Neuroprotection and RSI panels
Works offline as a web app

620+ usersfrom 22 countries

Open Najm ICUCalc

Neuroanatomy · Learning game

NeuroMaze

Can you find today’s lesion?

A neuroanatomy game for students, trainees and clinicians. Every day brings a new Daily Lesion: one localisation case for everyone, six tries, a result you can share. Around it: brainstem cross-sections where you place the lesion sign by sign, a visual field lab, pathways across the midline and bedside cases.

Daily Lesion · Lesion Placer · Visual Field Lab · Explorer · Tract Runner · Lesion Detective · Rapid Recall
37 levels across 12 regions, with spaced review and a rank ladder from Student to Professor
No account; progress stays on your device

Play today’s Daily Lesion Open NeuroMaze

Neurocritical care · Decision support

THERMIND

Fever is a clinical signal, not a diagnosis.

A learning and reasoning platform for fever after acute brain injury. It maps the thermoregulatory pathways, walks through infectious and non-infectious explanations with red flags first, and shows the evidence behind each step — and where it runs out. It will not label your patient “central fever” or “infection” for you.

Neuroanatomy: thermoregulatory pathways, interactive
Clinical Reasoning: six stages, red flags, a copyable note
Evidence and five teaching Clinical Cases

Open THERMIND Try a case